Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter

Ying Wu; Guohua Huang; Jinai He; Yutong Li

doi:doi:10.11648/j.ajns.20231202.14

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Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter

Ying Wu, Guohua Huang, Jinai He, Yutong Li

Published in American Journal of Nursing Science (Volume 12, Issue 2)

Received: 8 April 2023 Accepted: 26 April 2023 Published: 10 May 2023

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Abstract

Objective: This study investigated the effect of heparinized saline flushed catheter on preventing catheter-related thrombosis (CRT) among cancer patients received peripherally inserted central catheter (PICC) for chemotherapy. Background: CRT is a common and serious complication when using PICC, which is one of the most commonly used vascular access devices for drug infusion, intravenous nutrition, and chemotherapy. Methods: This prospective, paralled-group trial enrolled 300 cancer patients received chemotherapy who were randomly assigned to the intervention (n=150) or control (n=150) group. Besides the basic procedure of PICC combined with IC- ECG and B-mode ultrasound imaging, heparinized saline flushed catheters were used in the intervention group, while normal saline flushed ones were used in the control group. Hemorheology tests and tip sites measurements were used in outcome evaluation, and the incidences of CRT and other complications. In additions, thromboelastogram (TEG) were used to measure thrombus elastic before and one week after PICC. Results: 148 patients in the intervention group and 138 patients in the control group finished PICC and follow-ups, which indicating longer duration and more completion of PICC with better catheter tip positioning in the intervention group. Intervention subjects showed significant lower incidences of CRT and other complications (phlebitis, catheter blockage, catheter prolapse, and local infection) (P <.05). In additons, our proposed method may reduce CRT incidence via significantly improving blood circulation among patients received chemotherapy via PICC. Conclusion: Heparinized saline flushed catheter may increase chemotherapy completion quality via PICC, reduce the risk of catheter-related thrombosis complications, and reduce CRT incidence via improving blood circulation. Conclusions: This proposed method can be easily introduced to prolong the duration of the placement and improve the blood circulation of cancer patients received PICC.

Published in	American Journal of Nursing Science (Volume 12, Issue 2)
DOI	10.11648/j.ajns.20231202.14
Page(s)	44-49
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Heparinized, Saline, Flushing, Intracavitary, Electrocardiography, Catheter- Related Thrombosis

References

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APA Style

Ying Wu, Guohua Huang, Jinai He, Yutong Li. (2023). Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter. American Journal of Nursing Science, 12(2), 44-49. https://doi.org/10.11648/j.ajns.20231202.14

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ACS Style

Ying Wu; Guohua Huang; Jinai He; Yutong Li. Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter. Am. J. Nurs. Sci. 2023, 12(2), 44-49. doi: 10.11648/j.ajns.20231202.14

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AMA Style

Ying Wu, Guohua Huang, Jinai He, Yutong Li. Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter. Am J Nurs Sci. 2023;12(2):44-49. doi: 10.11648/j.ajns.20231202.14

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@article{10.11648/j.ajns.20231202.14,
  author = {Ying Wu and Guohua Huang and Jinai He and Yutong Li},
  title = {Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter},
  journal = {American Journal of Nursing Science},
  volume = {12},
  number = {2},
  pages = {44-49},
  doi = {10.11648/j.ajns.20231202.14},
  url = {https://doi.org/10.11648/j.ajns.20231202.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20231202.14},
  abstract = {Objective: This study investigated the effect of heparinized saline flushed catheter on preventing catheter-related thrombosis (CRT) among cancer patients received peripherally inserted central catheter (PICC) for chemotherapy. Background: CRT is a common and serious complication when using PICC, which is one of the most commonly used vascular access devices for drug infusion, intravenous nutrition, and chemotherapy. Methods: This prospective, paralled-group trial enrolled 300 cancer patients received chemotherapy who were randomly assigned to the intervention (n=150) or control (n=150) group. Besides the basic procedure of PICC combined with IC- ECG and B-mode ultrasound imaging, heparinized saline flushed catheters were used in the intervention group, while normal saline flushed ones were used in the control group. Hemorheology tests and tip sites measurements were used in outcome evaluation, and the incidences of CRT and other complications. In additions, thromboelastogram (TEG) were used to measure thrombus elastic before and one week after PICC. Results: 148 patients in the intervention group and 138 patients in the control group finished PICC and follow-ups, which indicating longer duration and more completion of PICC with better catheter tip positioning in the intervention group. Intervention subjects showed significant lower incidences of CRT and other complications (phlebitis, catheter blockage, catheter prolapse, and local infection) (P <.05). In additons, our proposed method may reduce CRT incidence via significantly improving blood circulation among patients received chemotherapy via PICC. Conclusion: Heparinized saline flushed catheter may increase chemotherapy completion quality via PICC, reduce the risk of catheter-related thrombosis complications, and reduce CRT incidence via improving blood circulation. Conclusions: This proposed method can be easily introduced to prolong the duration of the placement and improve the blood circulation of cancer patients received PICC.},
 year = {2023}
}

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TY  - JOUR
T1  - Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter
AU  - Ying Wu
AU  - Guohua Huang
AU  - Jinai He
AU  - Yutong Li
Y1  - 2023/05/10
PY  - 2023
N1  - https://doi.org/10.11648/j.ajns.20231202.14
DO  - 10.11648/j.ajns.20231202.14
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 44
EP  - 49
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20231202.14
AB  - Objective: This study investigated the effect of heparinized saline flushed catheter on preventing catheter-related thrombosis (CRT) among cancer patients received peripherally inserted central catheter (PICC) for chemotherapy. Background: CRT is a common and serious complication when using PICC, which is one of the most commonly used vascular access devices for drug infusion, intravenous nutrition, and chemotherapy. Methods: This prospective, paralled-group trial enrolled 300 cancer patients received chemotherapy who were randomly assigned to the intervention (n=150) or control (n=150) group. Besides the basic procedure of PICC combined with IC- ECG and B-mode ultrasound imaging, heparinized saline flushed catheters were used in the intervention group, while normal saline flushed ones were used in the control group. Hemorheology tests and tip sites measurements were used in outcome evaluation, and the incidences of CRT and other complications. In additions, thromboelastogram (TEG) were used to measure thrombus elastic before and one week after PICC. Results: 148 patients in the intervention group and 138 patients in the control group finished PICC and follow-ups, which indicating longer duration and more completion of PICC with better catheter tip positioning in the intervention group. Intervention subjects showed significant lower incidences of CRT and other complications (phlebitis, catheter blockage, catheter prolapse, and local infection) (P <.05). In additons, our proposed method may reduce CRT incidence via significantly improving blood circulation among patients received chemotherapy via PICC. Conclusion: Heparinized saline flushed catheter may increase chemotherapy completion quality via PICC, reduce the risk of catheter-related thrombosis complications, and reduce CRT incidence via improving blood circulation. Conclusions: This proposed method can be easily introduced to prolong the duration of the placement and improve the blood circulation of cancer patients received PICC.
VL  - 12
IS  - 2
ER  -

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Author Information

Ying Wu

Department of Venous Catheterization, The First Affiliated Hospital of Jinan University, Guangzhou, China
Guohua Huang

Department of Venous Catheterization, The First Affiliated Hospital of Jinan University, Guangzhou, China
Jinai He

Department of Venous Catheterization, The First Affiliated Hospital of Jinan University, Guangzhou, China
Yutong Li

Department of Venous Catheterization, The First Affiliated Hospital of Jinan University, Guangzhou, China

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Ying Wu, Guohua Huang, Jinai He, Yutong Li. (2023). Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter. American Journal of Nursing Science, 12(2), 44-49. https://doi.org/10.11648/j.ajns.20231202.14

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ACS Style

Ying Wu; Guohua Huang; Jinai He; Yutong Li. Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter. Am. J. Nurs. Sci. 2023, 12(2), 44-49. doi: 10.11648/j.ajns.20231202.14

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AMA Style

Ying Wu, Guohua Huang, Jinai He, Yutong Li. Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter. Am J Nurs Sci. 2023;12(2):44-49. doi: 10.11648/j.ajns.20231202.14

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@article{10.11648/j.ajns.20231202.14,
  author = {Ying Wu and Guohua Huang and Jinai He and Yutong Li},
  title = {Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter},
  journal = {American Journal of Nursing Science},
  volume = {12},
  number = {2},
  pages = {44-49},
  doi = {10.11648/j.ajns.20231202.14},
  url = {https://doi.org/10.11648/j.ajns.20231202.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajns.20231202.14},
  abstract = {Objective: This study investigated the effect of heparinized saline flushed catheter on preventing catheter-related thrombosis (CRT) among cancer patients received peripherally inserted central catheter (PICC) for chemotherapy. Background: CRT is a common and serious complication when using PICC, which is one of the most commonly used vascular access devices for drug infusion, intravenous nutrition, and chemotherapy. Methods: This prospective, paralled-group trial enrolled 300 cancer patients received chemotherapy who were randomly assigned to the intervention (n=150) or control (n=150) group. Besides the basic procedure of PICC combined with IC- ECG and B-mode ultrasound imaging, heparinized saline flushed catheters were used in the intervention group, while normal saline flushed ones were used in the control group. Hemorheology tests and tip sites measurements were used in outcome evaluation, and the incidences of CRT and other complications. In additions, thromboelastogram (TEG) were used to measure thrombus elastic before and one week after PICC. Results: 148 patients in the intervention group and 138 patients in the control group finished PICC and follow-ups, which indicating longer duration and more completion of PICC with better catheter tip positioning in the intervention group. Intervention subjects showed significant lower incidences of CRT and other complications (phlebitis, catheter blockage, catheter prolapse, and local infection) (P <.05). In additons, our proposed method may reduce CRT incidence via significantly improving blood circulation among patients received chemotherapy via PICC. Conclusion: Heparinized saline flushed catheter may increase chemotherapy completion quality via PICC, reduce the risk of catheter-related thrombosis complications, and reduce CRT incidence via improving blood circulation. Conclusions: This proposed method can be easily introduced to prolong the duration of the placement and improve the blood circulation of cancer patients received PICC.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Heparinized Saline Flushed Catheter May Reduce Risk of Thrombosis in Cancer Patients Received Chemotherapy with Peripherally Inserted Central Catheter
AU  - Ying Wu
AU  - Guohua Huang
AU  - Jinai He
AU  - Yutong Li
Y1  - 2023/05/10
PY  - 2023
N1  - https://doi.org/10.11648/j.ajns.20231202.14
DO  - 10.11648/j.ajns.20231202.14
T2  - American Journal of Nursing Science
JF  - American Journal of Nursing Science
JO  - American Journal of Nursing Science
SP  - 44
EP  - 49
PB  - Science Publishing Group
SN  - 2328-5753
UR  - https://doi.org/10.11648/j.ajns.20231202.14
AB  - Objective: This study investigated the effect of heparinized saline flushed catheter on preventing catheter-related thrombosis (CRT) among cancer patients received peripherally inserted central catheter (PICC) for chemotherapy. Background: CRT is a common and serious complication when using PICC, which is one of the most commonly used vascular access devices for drug infusion, intravenous nutrition, and chemotherapy. Methods: This prospective, paralled-group trial enrolled 300 cancer patients received chemotherapy who were randomly assigned to the intervention (n=150) or control (n=150) group. Besides the basic procedure of PICC combined with IC- ECG and B-mode ultrasound imaging, heparinized saline flushed catheters were used in the intervention group, while normal saline flushed ones were used in the control group. Hemorheology tests and tip sites measurements were used in outcome evaluation, and the incidences of CRT and other complications. In additions, thromboelastogram (TEG) were used to measure thrombus elastic before and one week after PICC. Results: 148 patients in the intervention group and 138 patients in the control group finished PICC and follow-ups, which indicating longer duration and more completion of PICC with better catheter tip positioning in the intervention group. Intervention subjects showed significant lower incidences of CRT and other complications (phlebitis, catheter blockage, catheter prolapse, and local infection) (P <.05). In additons, our proposed method may reduce CRT incidence via significantly improving blood circulation among patients received chemotherapy via PICC. Conclusion: Heparinized saline flushed catheter may increase chemotherapy completion quality via PICC, reduce the risk of catheter-related thrombosis complications, and reduce CRT incidence via improving blood circulation. Conclusions: This proposed method can be easily introduced to prolong the duration of the placement and improve the blood circulation of cancer patients received PICC.
VL  - 12
IS  - 2
ER  -

Copy | Download