| Peer-Reviewed

The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma

Received: 29 October 2021    Accepted: 15 November 2021    Published: 17 November 2021
Views:       Downloads:
Abstract

Papillary thyroid carcinoma (PTC) is one of the most common thyroid tumors in clinic. The incidence of papillary thyroid carcinoma is increasing year by year, especially in Cangzhou area, which brings great physical and mental pain to patients. Object: The understanding is further strengthened, and the level of diagnosis and treatment is improved, through the analysis of the biological and clinicopathological characteristics of papillary thyroid carcinoma. Method: Hospitalized cases with papillary thyroid carcinoma were collectedand biological and pathological characteristics were analyzed. Result: Among 110 cases of papillary thyroid carcinoma, 11 cases were male (10%), 99 cases were female (90%). There was no significant difference in invasiveness, lymph node metastasis, proportion of papillary microcarcinoma, number of lesions and involvement of glandular lobe, which were divided into groups according to different ages and different genders, (P>0.05). The average age of 46 cases with invasion was younger than that without invasion (P<0.001). There was less invasion and lymph node metastasis in papillary microcarcinoma (P<0.001). 16 cases of Hashimoto's thyroiditis were female, the average age of onset was higher, the difference was statistically significant (P<0.001) and TSH level was also higher than the patients without Hashimoto's thyroiditis (P<0.05). Conclusion: There was no significant difference in the clinicopathological characteristics of papillary thyroid carcinoma in different age groups and gender groups, but in the invasive study, the average age of patients with invasion was lower. Patients with papillary microcarcinoma are less likely to have invasion and lymph node metastasis. TSH levels are generally high in patients with Hashimoto's thyroiditis.

Published in American Journal of Biomedical and Life Sciences (Volume 9, Issue 6)
DOI 10.11648/j.ajbls.20210906.14
Page(s) 292-297
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Thyroid Papillary Carcinoma, Pathological Features, Analysis

References
[1] Li Tingting, Li Sumei, Xu Linlin. Epidemiological analysis of thyroid cancer and the value of ultrasound diagnosis [J]. Medical Information, 2020, 33 (05): 85-87.
[2] Weng Yihui, Cao Nong. Research progress of MT1-MMP and the invasion and metastasis of papillary thyroid carcinoma [J]. Medical Review, 2020, 26 (6): 1114-1118.
[3] Feng Hongfang, Chen Chuang, Sun Shengrong, Zheng Hongmei, Cao Tianze, Wei Wen, Tu Yi, Zhu Shan. Clinicopathological characteristics and summary analysis of 1585 cases of thyroid cancer [J]. Chinese Journal of Clinical Oncology, 2015, 42 (2): 77 -81.
[4] Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019 [J]. CA Cancer J Clin, 2019, 69 (1): 7-34.
[5] Lin Qingying, Chen Zhihui. Research progress on related influencing factors of thyroid cancer [J]. Chinese Journal of Endemic Disease Control, 2016, 31 (3): 260-263, 276.
[6] Valvo V, Nucera C. Coding molecular determinants of thyroid cancer development and progression [J]. Endocrinol Metab Clin North Am, 2019, 48 (1): 37-59.
[7] Du Qian, Yu Lili, Zhao Jing, SuYunxia, Zhang Luyu, Hou Zhaohong. Analysis of the clinical characteristics of 1393 cases of thyroid cancer [J]. Chinese Medical Records, 2016, 17 (2): 64-67.
[8] Kang Weiming, Wu Lian, Yu Jianchun, Ma Zhiqiang, Gao Weisheng. Retrospective clinical data analysis of thyroid disease spectrum of patients undergoing thyroid disease surgery in Peking Union Medical College Hospital from 1986 to 2012 [J]. Journal of Chinese Academy of Medical Sciences, 2013, 35 (4): 386-392.
[9] Gao Ming, Ge Minghua, Ji Qinghai, et al. Chinese expert consensus on the diagnosis and treatment of papillary thyroid microcarcinoma (2016 edition) [J]. Chinese Journal of Oncology, 2016, 43 (10): 405-411.
[10] Quan Peipei, Lu Yao, Shi Jianhua, et al. Study on the characteristics of papillary thyroid carcinoma based on age stratification [J]. Modern Diagnosis and Treatment, 2019, 30 (10): 1666-1668.
[11] Bray F, Ferlay J, Soerjomtaram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries [J]. CA Cancer J Clin, 2018, 68 (6): 394 - 424.
[12] Li Weiwei, Zhou Jinyi, Dong Jianmei, et al. Epidemiological status of thyroid cancer in Jiangsu Province in 2015 and analysis of trends from 2006 to 2015 [J]. Journal of Practical Oncology, 2021, 35 (1): 1-6.
[13] Wang Bin, Guo Tai, Yuan Shaoling. Analysis of related influencing factors of cervical lymph node metastasis in papillary thyroid carcinoma [J]. Journal of Shanxi Medical University, 2019, 50 (2): 202-205.
[14] Shen Jinfu, Li Juan, Wang Zhuoqun, et al. Analysis of influencing factors of lymph node metastasis in central area of papillary thyroid carcinoma [J]. Anhui Medicine, 2020, 41 (12): 1398 -1401.
[15] Li Chao, Cai Yongcong, Sun Ronghao. Papillary thyroid microcarcinoma: surgery or non-surgical active surveillance? [J]. Cancer Prevention and Treatment, 2019, 32 (12): 1045-1050.
[16] Liu Jianyun. Analysis of pathological characteristics of different types of papillary thyroid carcinoma [J]. Journal of Henan Medical College, 2019, 31 (6): 745-747.
[17] Ahmed R, Al-Shaikh S, Akhtar M. Hashimoto thyroiditis: a century later [J]. Advances In Anatomic Pathology, 2012, 19 (3): 181-186.
[18] Hirokawa M, Nishihara E, Takada N, et al. Warthin-like papillary thyroid carcinoma with immunoglobulin G4-positive plasma cells possibly related to Hashimoto’s thyroiditis [J]. Endocrine journal, 2018, 65 (2): 175-180.
[19] Liu Sanbao, Chen Bin. Research progress on the correlation between Hashimoto's thyroiditis with thyroid cancer and immune cells [J]. Journal of Liaoning Medical College, 2015, 36 (3): 103-105.
[20] Zhang Yan, Wang Wendong, Lan Xiabin, et al. Clinical study of papillary thyroid carcinoma with Hashimoto's thyroiditis [J]. Chinese Journal of Cancer, 2019, 29 (12): 948-954.
[21] Chen Jun, Wang Fuhua, Wang Yulin, et al. Study on the correlation between Hashimoto's thyroiditis and thyroid cancer [J]. Modern Instruments and Medical Care, 2019, 25 (1): 74-76, 80.
Cite This Article
  • APA Style

    Ying Li, Yi Su, Rong Qin Dai, Feng Zhou, Chao Shen, et al. (2021). The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma. American Journal of Biomedical and Life Sciences, 9(6), 292-297. https://doi.org/10.11648/j.ajbls.20210906.14

    Copy | Download

    ACS Style

    Ying Li; Yi Su; Rong Qin Dai; Feng Zhou; Chao Shen, et al. The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma. Am. J. Biomed. Life Sci. 2021, 9(6), 292-297. doi: 10.11648/j.ajbls.20210906.14

    Copy | Download

    AMA Style

    Ying Li, Yi Su, Rong Qin Dai, Feng Zhou, Chao Shen, et al. The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma. Am J Biomed Life Sci. 2021;9(6):292-297. doi: 10.11648/j.ajbls.20210906.14

    Copy | Download

  • @article{10.11648/j.ajbls.20210906.14,
      author = {Ying Li and Yi Su and Rong Qin Dai and Feng Zhou and Chao Shen and Zhong Yu Su and Gui Ran Yang},
      title = {The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma},
      journal = {American Journal of Biomedical and Life Sciences},
      volume = {9},
      number = {6},
      pages = {292-297},
      doi = {10.11648/j.ajbls.20210906.14},
      url = {https://doi.org/10.11648/j.ajbls.20210906.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20210906.14},
      abstract = {Papillary thyroid carcinoma (PTC) is one of the most common thyroid tumors in clinic. The incidence of papillary thyroid carcinoma is increasing year by year, especially in Cangzhou area, which brings great physical and mental pain to patients. Object: The understanding is further strengthened, and the level of diagnosis and treatment is improved, through the analysis of the biological and clinicopathological characteristics of papillary thyroid carcinoma. Method: Hospitalized cases with papillary thyroid carcinoma were collectedand biological and pathological characteristics were analyzed. Result: Among 110 cases of papillary thyroid carcinoma, 11 cases were male (10%), 99 cases were female (90%). There was no significant difference in invasiveness, lymph node metastasis, proportion of papillary microcarcinoma, number of lesions and involvement of glandular lobe, which were divided into groups according to different ages and different genders, (P>0.05). The average age of 46 cases with invasion was younger than that without invasion (PConclusion: There was no significant difference in the clinicopathological characteristics of papillary thyroid carcinoma in different age groups and gender groups, but in the invasive study, the average age of patients with invasion was lower. Patients with papillary microcarcinoma are less likely to have invasion and lymph node metastasis. TSH levels are generally high in patients with Hashimoto's thyroiditis.},
     year = {2021}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - The Analysis of Clinical Biological and Pathological Features in Papillary Thyroid Carcinoma
    AU  - Ying Li
    AU  - Yi Su
    AU  - Rong Qin Dai
    AU  - Feng Zhou
    AU  - Chao Shen
    AU  - Zhong Yu Su
    AU  - Gui Ran Yang
    Y1  - 2021/11/17
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ajbls.20210906.14
    DO  - 10.11648/j.ajbls.20210906.14
    T2  - American Journal of Biomedical and Life Sciences
    JF  - American Journal of Biomedical and Life Sciences
    JO  - American Journal of Biomedical and Life Sciences
    SP  - 292
    EP  - 297
    PB  - Science Publishing Group
    SN  - 2330-880X
    UR  - https://doi.org/10.11648/j.ajbls.20210906.14
    AB  - Papillary thyroid carcinoma (PTC) is one of the most common thyroid tumors in clinic. The incidence of papillary thyroid carcinoma is increasing year by year, especially in Cangzhou area, which brings great physical and mental pain to patients. Object: The understanding is further strengthened, and the level of diagnosis and treatment is improved, through the analysis of the biological and clinicopathological characteristics of papillary thyroid carcinoma. Method: Hospitalized cases with papillary thyroid carcinoma were collectedand biological and pathological characteristics were analyzed. Result: Among 110 cases of papillary thyroid carcinoma, 11 cases were male (10%), 99 cases were female (90%). There was no significant difference in invasiveness, lymph node metastasis, proportion of papillary microcarcinoma, number of lesions and involvement of glandular lobe, which were divided into groups according to different ages and different genders, (P>0.05). The average age of 46 cases with invasion was younger than that without invasion (PConclusion: There was no significant difference in the clinicopathological characteristics of papillary thyroid carcinoma in different age groups and gender groups, but in the invasive study, the average age of patients with invasion was lower. Patients with papillary microcarcinoma are less likely to have invasion and lymph node metastasis. TSH levels are generally high in patients with Hashimoto's thyroiditis.
    VL  - 9
    IS  - 6
    ER  - 

    Copy | Download

Author Information
  • Department of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, China

  • Thyroid and Breast Surgical Department, People's Hospital of Nanpi County, Cangzhou, China

  • Department of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, China

  • Department of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, China

  • Department of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, China

  • Department of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, China

  • Department of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, ChinaDepartment of Medical Technology Laboratory, Cangzhou Medical College, Cangzhou, China

  • Sections