Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles

Koffi Konan Sylvestre; Kambiré Ollo; Gnamba Corneil Quand-même; Kimou Kouakou Jocelin; Berté Mohamed; Kouadio Kouakou Etienne; Koné Souleymane; Ouattara Lassiné

doi:doi:10.11648/j.ajac.20231104.12

Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles

Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, Kouadio Kouakou Etienne, Koné Souleymane, Ouattara Lassiné

Published in American Journal of Applied Chemistry (Volume 11, Issue 4)

Received: 8 July 2023 Accepted: 2 August 2023 Published: 28 August 2023

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Abstract

Persistent organic pollutants such as pharmaceuticals (iohexol and paracetamol) released into the environment is an environmental problem. Thus our objective is to propose an effective and less expensive method for the determination of their concentrations in the environment. In this work the detection and quantification of pharmaceuticals (iohexol and paracetamol) were performed using cyclic voltammetry and differential pulse voltammetry (DPV). The anode used is a boron-doped diamond electrode (BDD) modified with gold particles (Au-BDD). The characterization of the Au-BDD electrode surface by scanning electron microscopy coupled to energy dispersive spectroscopy and by the electrochemical method (cyclic voltammetry) showed the presence of gold particles uniformly distributed on the anode surface. DPV method allowed to obtain two calibration curves for iohexol and paracetamol concentrations ranging respectively from 4 µM to 67.42 µM and from 0.8 µM to 22.943 µM. The limits of detection are respectively 1.13 µM and 0.045 µM for iohexol and paracetamol. These results show that the presence of gold particles on the anode surface improved the detection of paracetamol. These pharmaceuticals were detected in an ionic environment and it was noted that the interference phenomenon was very negligible during the detection of these two pharmaceuticals. This shows that our anode can be used to determine PCM and IHX concentrations in highly charged media.

Published in	American Journal of Applied Chemistry (Volume 11, Issue 4)
DOI	10.11648/j.ajac.20231104.12
Page(s)	103-111
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Detection, Paracetamol, Iohexol, Gold, Voltammetry

References

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Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, et al. (2023). Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. American Journal of Applied Chemistry, 11(4), 103-111. https://doi.org/10.11648/j.ajac.20231104.12

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ACS Style

Koffi Konan Sylvestre; Kambiré Ollo; Gnamba Corneil Quand-même; Kimou Kouakou Jocelin; Berté Mohamed, et al. Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. Am. J. Appl. Chem. 2023, 11(4), 103-111. doi: 10.11648/j.ajac.20231104.12

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AMA Style

Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, et al. Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. Am J Appl Chem. 2023;11(4):103-111. doi: 10.11648/j.ajac.20231104.12

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@article{10.11648/j.ajac.20231104.12,
  author = {Koffi Konan Sylvestre and Kambiré Ollo and Gnamba Corneil Quand-même and Kimou Kouakou Jocelin and Berté Mohamed and Kouadio Kouakou Etienne and Koné Souleymane and Ouattara Lassiné},
  title = {Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles},
  journal = {American Journal of Applied Chemistry},
  volume = {11},
  number = {4},
  pages = {103-111},
  doi = {10.11648/j.ajac.20231104.12},
  url = {https://doi.org/10.11648/j.ajac.20231104.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231104.12},
  abstract = {Persistent organic pollutants such as pharmaceuticals (iohexol and paracetamol) released into the environment is an environmental problem. Thus our objective is to propose an effective and less expensive method for the determination of their concentrations in the environment. In this work the detection and quantification of pharmaceuticals (iohexol and paracetamol) were performed using cyclic voltammetry and differential pulse voltammetry (DPV). The anode used is a boron-doped diamond electrode (BDD) modified with gold particles (Au-BDD). The characterization of the Au-BDD electrode surface by scanning electron microscopy coupled to energy dispersive spectroscopy and by the electrochemical method (cyclic voltammetry) showed the presence of gold particles uniformly distributed on the anode surface. DPV method allowed to obtain two calibration curves for iohexol and paracetamol concentrations ranging respectively from 4 µM to 67.42 µM and from 0.8 µM to 22.943 µM. The limits of detection are respectively 1.13 µM and 0.045 µM for iohexol and paracetamol. These results show that the presence of gold particles on the anode surface improved the detection of paracetamol. These pharmaceuticals were detected in an ionic environment and it was noted that the interference phenomenon was very negligible during the detection of these two pharmaceuticals. This shows that our anode can be used to determine PCM and IHX concentrations in highly charged media.},
 year = {2023}
}

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TY  - JOUR
T1  - Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles
AU  - Koffi Konan Sylvestre
AU  - Kambiré Ollo
AU  - Gnamba Corneil Quand-même
AU  - Kimou Kouakou Jocelin
AU  - Berté Mohamed
AU  - Kouadio Kouakou Etienne
AU  - Koné Souleymane
AU  - Ouattara Lassiné
Y1  - 2023/08/28
PY  - 2023
N1  - https://doi.org/10.11648/j.ajac.20231104.12
DO  - 10.11648/j.ajac.20231104.12
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 103
EP  - 111
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20231104.12
AB  - Persistent organic pollutants such as pharmaceuticals (iohexol and paracetamol) released into the environment is an environmental problem. Thus our objective is to propose an effective and less expensive method for the determination of their concentrations in the environment. In this work the detection and quantification of pharmaceuticals (iohexol and paracetamol) were performed using cyclic voltammetry and differential pulse voltammetry (DPV). The anode used is a boron-doped diamond electrode (BDD) modified with gold particles (Au-BDD). The characterization of the Au-BDD electrode surface by scanning electron microscopy coupled to energy dispersive spectroscopy and by the electrochemical method (cyclic voltammetry) showed the presence of gold particles uniformly distributed on the anode surface. DPV method allowed to obtain two calibration curves for iohexol and paracetamol concentrations ranging respectively from 4 µM to 67.42 µM and from 0.8 µM to 22.943 µM. The limits of detection are respectively 1.13 µM and 0.045 µM for iohexol and paracetamol. These results show that the presence of gold particles on the anode surface improved the detection of paracetamol. These pharmaceuticals were detected in an ionic environment and it was noted that the interference phenomenon was very negligible during the detection of these two pharmaceuticals. This shows that our anode can be used to determine PCM and IHX concentrations in highly charged media.
VL  - 11
IS  - 4
ER  -

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Author Information

Koffi Konan Sylvestre

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
Kambiré Ollo

Science and Technology Training and Research Unit, University of Man, Man, Côte d’Ivoire
Gnamba Corneil Quand-même

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
Kimou Kouakou Jocelin

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
Berté Mohamed

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
Kouadio Kouakou Etienne

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
Koné Souleymane

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire
Ouattara Lassiné

Matter Constitution and Reaction Laboratory, Training and Research Unit of Structural Sciences of Matter and Technology, Félix Houphouët-Boigny University, Abidjan, Côte d’Ivoire

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APA Style

Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, et al. (2023). Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. American Journal of Applied Chemistry, 11(4), 103-111. https://doi.org/10.11648/j.ajac.20231104.12

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ACS Style

Koffi Konan Sylvestre; Kambiré Ollo; Gnamba Corneil Quand-même; Kimou Kouakou Jocelin; Berté Mohamed, et al. Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. Am. J. Appl. Chem. 2023, 11(4), 103-111. doi: 10.11648/j.ajac.20231104.12

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AMA Style

Koffi Konan Sylvestre, Kambiré Ollo, Gnamba Corneil Quand-même, Kimou Kouakou Jocelin, Berté Mohamed, et al. Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles. Am J Appl Chem. 2023;11(4):103-111. doi: 10.11648/j.ajac.20231104.12

Copy | Download

@article{10.11648/j.ajac.20231104.12,
  author = {Koffi Konan Sylvestre and Kambiré Ollo and Gnamba Corneil Quand-même and Kimou Kouakou Jocelin and Berté Mohamed and Kouadio Kouakou Etienne and Koné Souleymane and Ouattara Lassiné},
  title = {Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles},
  journal = {American Journal of Applied Chemistry},
  volume = {11},
  number = {4},
  pages = {103-111},
  doi = {10.11648/j.ajac.20231104.12},
  url = {https://doi.org/10.11648/j.ajac.20231104.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20231104.12},
  abstract = {Persistent organic pollutants such as pharmaceuticals (iohexol and paracetamol) released into the environment is an environmental problem. Thus our objective is to propose an effective and less expensive method for the determination of their concentrations in the environment. In this work the detection and quantification of pharmaceuticals (iohexol and paracetamol) were performed using cyclic voltammetry and differential pulse voltammetry (DPV). The anode used is a boron-doped diamond electrode (BDD) modified with gold particles (Au-BDD). The characterization of the Au-BDD electrode surface by scanning electron microscopy coupled to energy dispersive spectroscopy and by the electrochemical method (cyclic voltammetry) showed the presence of gold particles uniformly distributed on the anode surface. DPV method allowed to obtain two calibration curves for iohexol and paracetamol concentrations ranging respectively from 4 µM to 67.42 µM and from 0.8 µM to 22.943 µM. The limits of detection are respectively 1.13 µM and 0.045 µM for iohexol and paracetamol. These results show that the presence of gold particles on the anode surface improved the detection of paracetamol. These pharmaceuticals were detected in an ionic environment and it was noted that the interference phenomenon was very negligible during the detection of these two pharmaceuticals. This shows that our anode can be used to determine PCM and IHX concentrations in highly charged media.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Electrochemical Detection of Paracetamol and Iohexol Using a Boron-Doped Diamond Anode Modified with Gold Particles
AU  - Koffi Konan Sylvestre
AU  - Kambiré Ollo
AU  - Gnamba Corneil Quand-même
AU  - Kimou Kouakou Jocelin
AU  - Berté Mohamed
AU  - Kouadio Kouakou Etienne
AU  - Koné Souleymane
AU  - Ouattara Lassiné
Y1  - 2023/08/28
PY  - 2023
N1  - https://doi.org/10.11648/j.ajac.20231104.12
DO  - 10.11648/j.ajac.20231104.12
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 103
EP  - 111
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20231104.12
AB  - Persistent organic pollutants such as pharmaceuticals (iohexol and paracetamol) released into the environment is an environmental problem. Thus our objective is to propose an effective and less expensive method for the determination of their concentrations in the environment. In this work the detection and quantification of pharmaceuticals (iohexol and paracetamol) were performed using cyclic voltammetry and differential pulse voltammetry (DPV). The anode used is a boron-doped diamond electrode (BDD) modified with gold particles (Au-BDD). The characterization of the Au-BDD electrode surface by scanning electron microscopy coupled to energy dispersive spectroscopy and by the electrochemical method (cyclic voltammetry) showed the presence of gold particles uniformly distributed on the anode surface. DPV method allowed to obtain two calibration curves for iohexol and paracetamol concentrations ranging respectively from 4 µM to 67.42 µM and from 0.8 µM to 22.943 µM. The limits of detection are respectively 1.13 µM and 0.045 µM for iohexol and paracetamol. These results show that the presence of gold particles on the anode surface improved the detection of paracetamol. These pharmaceuticals were detected in an ionic environment and it was noted that the interference phenomenon was very negligible during the detection of these two pharmaceuticals. This shows that our anode can be used to determine PCM and IHX concentrations in highly charged media.
VL  - 11
IS  - 4
ER  -

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